| The Vitiligo is a plural disease often presents after | | | | oxide in the tissue of 25 patients with generalized |
| suffering strong impressions or in the presence of | | | | vitiligo in 25 cases and controls. These enzymes |
| a situation of stress. This condition is triggered in | | | | and compounds involved in the metabolism of |
| genetically predisposed individuals a neural | | | | eliminating free radicals. |
| response (neurochemistry) which destroys the | | | | The results revealed a significant increase in the |
| melanocytes showed the presence of an excess | | | | level of superoxide dismutase, glutathione |
| of free radicals in the areas of depigmentation | | | | peroxidase and malondialdehyde in patients with |
| phase when melanin becomes toxic to the cells | | | | generalized vitiligo (P 0.05). We conclude that the |
| that produced them. Taking antioxidant vitamins | | | | imbalance of tissue oxidation-reduction system |
| and minerals are highly recommended to enhance | | | | with production of free radicals is an initial |
| treatment Melagenina Plus. | | | | pathogenic event in the degeneration of melanotic |
| The toxins are accumulated in the liver and all | | | | vitiligo. |
| those bodies responsible for their elimination, and | | | | Antioxidants are substances that act to protect |
| this leads to remain undifferentiated melanocytes | | | | cells from destruction by the chain reaction of |
| in the basal layer as a result of lack of blood flow, | | | | electrons (cell death) caused by free radicals. |
| leading to the melanocytes lose their functions | | | | Antioxidants are vitamins A, E, C, etc, and in |
| and remain in the basal cells as undifferentiated (ie | | | | minerals such as zinc, selenium and copper as well |
| no function to produce melanin which becomes | | | | as compounds found in fruits and vegetables. The |
| progressive depigmentation of the skin), and this | | | | main functions of human skin are: |
| coupled with the inability to acquire keratinocytes | | | | Vitamin A (retinoids): Normalizes keratinization: |
| retain little melanin that is produced. Such injuries | | | | decreases sebum production in acne, reverses |
| are generally amplified when the carrier becomes | | | | sun damage and deals, stretch marks and cellulite. |
| aware that the majority of medical professionals | | | | Vitamin D (and anlogs): Regulates the skin's |
| judge the condition as incurable. | | | | immune system, regulates epithelial proliferation |
| As part of the accumulation of these residues in | | | | and promotes differentiation. |
| the liver, the symptoms that arise are often | | | | Vitamin C: Antioxidant; regulates the synthesis of |
| present in these patients, such as headaches, | | | | collagen, formation of the lipid barrier of the |
| abdominal pain, reluctance, depression, and itching | | | | stratum corneum, regenerates vitamin E, provides |
| in areas of injury, hearing loss (may be all present | | | | photoprotection (in combination with vitamin E). |
| as only one of them). | | | | Vitamin E: Membrane antioxidant, protects against |
| Besides the excess of free radicals (toxins) has, | | | | oxidative injury, provides photoprotection (along |
| among other sources, excessive sunlight and skin | | | | with vitamin C). |
| burns. | | | | Coenzyme Q: Membrane antioxidant, regenerates |
| Has been related to oxidative stress in the | | | | vitamin E, protects against photoaging. |
| pathogenesis of vitiligo. In one study, we | | | | Others: Minerals such as Zinc, Copper, flavonoids, |
| examined the levels of superoxide dismutase, | | | | antioxidants, etc. |
| glutathione peroxidase, malondialdehyde and nitric | | | | |